We are living in a time in which the “made” and the “born” are fusing. Hypoallergenic cats are already on the market. Plants are used as sensors, information displays and chemical factories. Animals are being augmented and branded. Plastic surgeons sculpt flesh to match retouched photographs in glossy magazines. In response to donar organ shortages, researchers are working on a 3D organ printer. Real nature is not green. It is out of control. Our technological world has become so intricate and uncontrollable that it has become a nature of its own. Games have become jobs. Second life is not sustainable. Digital world metaphors boomerang into our physical environment. Wine making has become an information science. Everyday robots give massages and take care of the children. RFID chips open doors, they might be infected, but nonetheless are edible. How should we relate to these developments? How will we design? How will we build? How do we relate to our environment? How can we create humane technology?